OMNISENSE 7000S/8000S

Bone Assessment at
Multiple Skeletal Sites

 

The Multi-Site Advantage

Sunlight OmnisenseTM 7000S is the only multi-site bone sonometer available worldwide. This unique advantage is crucial in the diagnosis of osteoporosis, a systemic disease that involves the deterioration of bone in the entire skeleton. Osteoporosis strikes different bones at different rates. It is therefore important for the physician to test bone strength at various skeletal sites in order to increase confidence in the prediction of fracture risk for osteoporotic patients.

Combining Measurement Sites – A Proven Benefit

Diagnosis of osteoporosis at multiple sites is a well-established procedure in X-ray-based technologies.[i],[ii],[iii],[iv]Omnisense is the only bone sonometer that is capable of assessing bone strength at a number of proven skeletal sites, an innovation that brings multi-site measurement to primary care facilities with safe, user-friendly equipment.[v]

Testing at multiple sites reveals additional important skeletal information to the physician. It enables the testing of bones with different combinations of cortical and cancellous bone and weight-bearing and non-weight-bearing bone, and thus provides a more comprehensive analysis of the skeleton. Information from several sites is also useful in the monitoring of treatment for osteoporosis[vi], because different bones reflect changes after treatment at different rates.2,4,[vii]

The use of multi-site measurement also provides better measurement sensitivity than single site, increasing the likelihood of osteoporosis detection in the individual patient.5,7,[viii],[ix]As in X-ray-based assessment, the accepted clinical measurement method uses the lower T-score between the results at the two sites as the diagnostic score. In the study recording the collection of the Omnisense reference database[x],[xi], multi-site measurement found a significantly higher prevalence of women with an osteoporotic T-score (T-score <-2.5) than measurement at any single site. 

Improved Measurement Flexibility

Multi-site measurement is essential for patients who cannot be measured at a particular measurement site. Obesity, edema at a particular site, a previous fracture, or an IV line can all cause difficulties in measuring a patient’s SOS at a specific site. While measurement problems at one measurement site are revealed in five percent of patients, 99 percent of patients can be measured in at least one of the Sunlight OmnisenseTM measurement sites.4

Three Informative Skeletal Sites

Radius 

The third distal radius (wrist) is a measurement site that boasts a wealth of clinical data showing its efficacy in predicting fracture risk. In addition, a number of cross-sectional studies5,[xii]  found that measurements at this site significantly discriminate between fractured and non-fractured subjects. These findings clearly demonstrate Omnisense’s capability to detect osteoporosis.

Phalanx

The 3rd proximal phalanx (finger) is a site clinically proven to predict fracture risk.10,11,[xiii] Measurement at the phalanx is particularly useful when combined with measurement from the radius, since differences in cortical thickness at the two sites provide more information, creating a more comprehensive picture of bone health.

Metatarsus

Measurements at the 5th metatarsus (foot), a weight-bearing bone, have been shown to be useful in the assessment of fracture risk.11 Measurement at this site is particularly important because weight-bearing bone may lose strength at a different rate than non-weight-bearing bone.

References:



[i] Cummings, S.R., D.M. Black, M.C. Nevitt, et. al., “Bone Mineral Density at various Sites for Prediction of Hip Fractures,” Lancet 1993, 341:72-75

[ii] Davis, J.W., R.D. Ross, R.D. Wasnich, “Evidence for Both Generalized and Regional Low Bone Mass among Elderly Women, Journal of Bone Mineral Research, 1994, 9:305-309

[iii] Ross, P.D., H.K. Genant, J.W. Davis, P.D. Miller, R.D. Wasnich, “Predicting Vertebral Fracture Incidence from Prevalent Fractures and Bone Density among Non-black, Osteoporotic Women,” Osteoporosis International, 1993, 3:120-126

[iv] Njeh, C.F., I. Saeed, M. Grigorian, D.L. Kendler, B. Fan, J. Shepherd, M. McClung, W. Drake, and H.K. Genant, “Assessment of Bone Status Using Speed of Sound at Multiple Sites,” Bone, December 2000

[v] Barkmann, R., E. Kantrovich, C. Singal, D. Hans, H.K. Genant, M. Heller, and C.C. Glüer, “A New Method for Quantitative Ultrasound Measurements at Multiple Skeletal Sites,” Journal of Clinical Densitometry, Volume 3, No. 1, 1-7, Spring 2000 

[vi] Weiss, M., A. Ben Shlomo, P. Hagag, M. Rapoport, and S. Ish-Shalom, “Effect of Estrogen Replacement Therapy on Speed of Sound at Multiple Skeletal Sites,” Maturitas 35 (2000), 237-243

[vii] Hans, D., S.K. Srikastav, C. Singal, R. Barkmann, C.F. Njeh, E. Kantrovich, C.C. Glüer, H.K. Genant, “Does Combining the Results from Multiple Bone Sites Measured by a New Quantitative Ultrasound Device Improve Discrimination of Hip Fracture?”, Journal of Bone and Mineral Research, Volume 14, No. 4, 1999

[viii] Abrahamson, B., T.B. Hansen, B. Bjørn Jensen, A.P. Hermann, P. Eiken, “Site of Osteodensitometry in Perimenopausal Women: Correlation and Limits of Agreement between Anatomic Regions,” Journal of Bone Mineral Research, 1997, 12:1471-1479

[ix] Melton, L.J., III, “How Many Women Have Osteoporosis Now?” Journal of Bone Mineral Research, 1994, 9:305-309

[x] Knapp, K., G.M. Blake, T.D. Spector, and I. Fogelman, “Multi-Site Quantitative Ultrasound: Precision, Age, and Menopause Related Changes, Fracture Discrimination, and T-Score Equivalence with DXA,” Osteoporosis International 12 (2001), 6:456-464 

[xi] Weiss, M., A.B. Ben-Shlomo, P. Hagag, and M. Rapoport, “Reference Database for Bone Speed of Sound Measurement by a Novel Quantitative Multi-Site Ultrasound Device,” Osteoporosis International 11 (2000), 8: 688-696

[xii] Weiss, M., A. Ben-Shlomo, P. Hagag, and S. Ish-Shalom, “Discrimination of Proximal Hip Fracture by Quantitative Ultrasound Measurement at the Radius,” Osteoporosis International 11(2000) 5:411-416

[xiii] Njeh, C.F., C. Wu, B. Fan, D. Hans, T. Fuerst, Y. He, J. Richards, P. Augat, and H.K. Genant, “Estimation of Wrist Fracture Load Using Phalangeal Speed of Sound: An In-Vitro Study,” In Press

 

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Osteoporosis
Bone Densitome
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''For better prevention, detection, diagnosis,
and treatments of Osteoporosis''

278 S. Lincoln St., Minster, OH 45865
Phone: 1-888-999-4774
Fax: 1-419-628-4005
Email: info@bonedensitometry.com

Message from the MEC/OBD president:

"As president, I have committed my company to providing medical facilities with "state-of-the-art" bone densitometry equipment to help them do a better job with preventing, testing for, screening for, detecting, diagnosing, and treating Osteoporosis which ravage so many women and men. Our diagnostic equipment will speed up the prevention, detection, diagnosis, and treatment of Osteoporosis and osteoporotic bone disorders in men and women. The key to preventing Osteoporosis in women and men is early detection, diagnosis, and treatment. This means measuring, testing, screening, detecting, and diagnosing low bone mass in women and men early in their lifetimes so that effective treatment can stop the Osteoporosis dead in its tracks." Together, we can help protect families from this terrible disease.

Sincerely,
Mark Piening

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